Lesinurad/Allopurinol 200/300 FDC Tablets Bioequivalence

Exclusion Criteria

• - Asian subject who has a positive test for the HLA-B*5801 allele.
• - History or suspicion of kidney stones.
• - Estimated creatinine clearance, as determined at Screening, of < 90 mL/min calculated by the Cockcroft-Gault formula using ideal body weight.
• - Undergone major surgery within 3 months prior to Screening.
• - Donated blood or experienced significant blood loss (> 450 mL) within 12 weeks prior to Day 1or has given a plasma donation within 4 weeks prior to Day 1.
• - Inadequate venous access or unsuitable veins for repeated venipuncture.
• - Received any strong or moderate enzyme-inducing drug or product within 2 months prior to Screening