Single dose study to assess efficacy and safety of 4 doses of LAS100977 in chronic obstructive pulmonary disease (COPD) population

Exclusion Criteria

• 1. History or current diagnosis of asthma.
• 2. A respiratory tract infection or COPD exacerbation in the six weeks prior to the screening visit.
• 3. Patients who have been hospitalised for an acute COPD exacerbation in the 3 months prior to screening visit.
• 4. Clinically significant respiratory conditions other than COPD condition.
• 5. Clinically significant cardiovascular conditions.
• 6. Patients unable to properly use a dry powder or pMDI inhaler device or unable to perform acceptable spirometry.
• 7. Clinically relevant abnormalities laboratory, ECG parameters or physical examination results at the screening evaluation that in the investigator's opinion, preclude study participation.
• 8. Patients who intend to use any concomitant medication not permitted by this protocol or who have not undergone the required washout period for a particular prohibited medication.