A Drug-Drug Interaction Study to study the effect of AZD1981 on Warfarin

Study identifier:D9830C00017

ClinicalTrials.gov identifier:N/A

EudraCT identifier:2010-021956-24

CTIS identifier:N/A

Study Complete

Official Title

A Phase I, Open Label, Randomised, Parallel Group Study of Repeated Oral Doses of AZD1981 (100 mg Twice Daily and 400 mg Twice Daily) for Two Weeks and Single Doses of Warfarin (25 mg) to Evaluate the Pharmacokinetic Interaction of AZD1981 and Warfarin and the Effect of AZD1981 on Warfarin Pharmacodynamics in Healthy Male Volunteers

Medical condition

pharmakokinetic

Phase

Phase 1

Healthy volunteers

Yes

Study drug

AZD1981, Warfarin

Sex

Male

Actual Enrollment

28

Study type

Interventional

Age

18 Years - 55 Years

Date

Study Start Date: 01 Oct 2010
Primary Completion Date: 01 Dec 2010
Study Completion Date: 01 Dec 2010

Study design

Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Basic Science

Verification:

Verified 01 Nov 2013 by AstraZeneca Pharmaceuticals

Sponsors

AstraZeneca Pharmaceuticals

Collaborators

-

Inclusion and exclusion criteria