Study in healthy volunteers to investigate the effects of Diltiazem on the Pharmacokinetics of naloxegol

Study identifier:D3820C00032

ClinicalTrials.gov identifier:N/A

EudraCT identifier:N/A

CTIS identifier:N/A

Study Complete

Official Title

An Open-label, sequential, 3-period study to Assess the Effects of Diltiazem on the Pharmacokinetics of Naloxegol in Healthy Subjects

Medical condition

Drug induced constipation

Phase

Phase 1

Healthy volunteers

Yes

Study drug

Naloxegol, Diltiazem XR

Sex

All

Actual Enrollment

44

Study type

Interventional

Age

18 Years - 55 Years

Date

Study Start Date: 01 May 2012
Primary Completion Date: 01 Aug 2012
Study Completion Date: 01 Aug 2012

Study design

Allocation: Non-randomized
Endpoint Classification: Safety Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science

Verification:

Verified 01 Oct 2014 by AstraZeneca

Sponsors

AstraZeneca

Collaborators

-

Inclusion and exclusion criteria