This study will assess the safety and tolerability of AZD8418 after single increasing oral doses

Study identifier:D2590C00001

ClinicalTrials.gov identifier:N/A

EudraCT identifier:N/A

CTIS identifier:N/A

Terminated/Withdrawn

Official Title

A Phase I, Single-center, Randomized, Double-blind, Placebo-controlled Single-ascending Dose, First Time Into Man Study to Assess the Safety, Tolerability, and Pharmacokinetics (Part A) and an Open-label Assessment of the Effect of Food on the Pharmacokinetics (Part B) of Orally Administered AZD8418

Medical condition

Healthy

Phase

Phase 1

Healthy volunteers

Yes

Study drug

AZD8418, Placebo

Sex

All

Actual Enrollment

40

Study type

Interventional

Age

18 Years - 45 Years

Date

Study Start Date: 01 Nov 2009
Primary Completion Date: 01 Mar 2010
Study Completion Date: 01 Mar 2010

Study design

Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Double Blind
Primary Purpose: Basic Science

Verification:

Verified 01 Nov 2013 by AstraZeneca Pharmaceuticals

Sponsors

AstraZeneca Pharmaceuticals

Collaborators

-

Inclusion and exclusion criteria