PK Study of PT003 and PT001 in Japanese Healthy Subjects

Exclusion Criteria

• -Pregnancy, nursing female subjects, or subjects trying to conceive
• -Clinically significant neurologic, cardiovascular, hepatic, renal, endocrinologic, pulmonary, hematological, psychiatric, or other medical illness that would interfere with participation in this study
• -History of ECG abnormalities
• -Cancer not in complete remission for at least 5 years
• -Clinically significant, symptomatic prostatic hypertrophy
• -Male subjects with a trans-urethral resection of the prostate or full resection of the prostate within 6 months prior to Screening
• -Clinically significant bladder neck obstruction or urinary retention
• -Inadequately treated glaucoma
• -History of an allergic reaction or hypersensitivity to any drug or to any component of the formulations used in this study
• -Subjects with pre-existing anemia and/or iron deficiency