Dapagliflozin Evaluation in Patients with Inadequately Controlled Type 1 Diabetes - DEPICT 1

Exclusion Criteria

• •History of Type 2 Diabetes mellitus (T2DM) or maturity onset diabetes of the young (MODY), pancreatic surgery, or chronic pancreatitis that could result in decreased beta cell capacity
• •Taking metformin and/or thiazolidinediones within 2 months prior to screening
• •Taking any antidiabetic medication (other than insulin), within 1 month prior to screening
• - Taking GLP-1 receptor agonist within 2 months prior to screening for once weekly administration and within 1 month prior to screening for once or twice daily administration
• •History of diabetes ketoacidosis requiring medical intervention within 1 month prior to screening
• •History of hospital admission for glycemic control (either hyperglycemia or hypoglycemia) within 1 month prior to screening
• •Frequent episodes of severe hypoglycemia (more than one episode requiring medical assistance, emergency care), and/or glucagon therapy administered by a third-party individual within 1 month prior to screening
• •History of Addison's disease