Study identifier:D5680C00003
ClinicalTrials.gov identifier:NCT04675034
EudraCT identifier:N/A
CTIS identifier:N/A
: A Randomised, Double-blind, Placebo-controlled, Dose-response Study of the Efficacy and Safety of MEDI7352 in Subjects with Painful Osteoarthritis of the Knee:
Painful osteoarthritis of the knee
Phase 2
No
-
All
345
Interventional
18 Years - 80 Years
Allocation: Randomized
Endpoint Classification: -
Intervention Model: Parallel Assignment
Masking: -
Primary Purpose: Treatment
Verified 01 Dec 2022 by AstraZeneca
AstraZeneca
-
No locations available
Arms | Assigned Interventions |
---|---|
Experimental: Cohort 1 Dose A: MEDI7352 Q2W | Biological/Vaccine: MEDI7352 Dose A: MEDI7352 Q2W |
Experimental: Cohort 2 Dose B: MEDI7352 Q2W | Biological/Vaccine: MEDI7352 Dose B: MEDI7352 Q2W |
Experimental: Cohort 3 Dose C: MEDI7352 Q2W | Biological/Vaccine: MEDI7352 Dose C: MEDI7352 Q2W |
Experimental: Cohort 4 Dose D: MEDI7352 Q2W | Biological/Vaccine: MEDI7352 Dose D: MEDI7352 Q2W |
Placebo Comparator: Cohort 5: Placebo to match MEDI7352 Q2W | Biological/Vaccine: Placebo Placebo to match MEDI7352 Q2W |