A Multicentre, Open-label, Randomized, 6-week, Phase IV Study of the Onset and Maintenance of the Antiplatelet Effect of Ticagrelor Compared with Clopidogrel with Aspirin as Background Therapy in Chinese Patients with Non-ST or ST Elevation Acute Coronary Syndromes (ACS)
Non-ST or ST Elevation Acute Coronary Syndromes
18 Years - 150 Years
Endpoint Classification: Pharmacodynamics Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Verified 01 Feb 2015 by AstraZeneca
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90mg tablets. loading dose of 180mg ticagrelor tablets (two 90mg tablets) taken orally, followed by 90mg of ticagrelor 12 hours after the first dose. Duration of treatment: 6 weeks.
|Active Comparator: clopidogrel|
75mg capsule. loading dose of 600mg clopidogrel capsules (eight 75mg capsules) taken orally, follow by 75mg of clopidogrel capsules orally od. Duration of treatment: 6 weeks.