A study comparing Ceftazidime-Avibactam versus Meropenem in hospitalized adults with nosocomial pneumonia

Inclusion Criteria

• - 18 to 90 years of age inclusive
• - Females can participate if surgically sterile or completed menopause; if able to have children, must have negative serum pregnancy test, agree not to attempt pregnancy and use acceptable contraception while receiving study therapy and for 1 week after
• - Onset of symptoms ≥ 48 hours after admission or <7 days after discharge from an inpatient acute or chronic care facility
• - New or worsening infiltrate on chest X-ray obtained within 48 hours prior to randomization
• - At least 1 of the following systemic signs:Fever (temperature >38 C) or hypothermia (rectal/core temperature <35 C); White blood cell count >10,000 cells/mm3, or White blood cell count <4500 cells/mm3, or >15% band forms.