A study to Assess the Safety, Tolerability and Pharmacokinetics after Single Ascending Intravenous Doses of AZD2927 in Healthy Male volunteers

Exclusion Criteria

• - History of any clinically significant disease or disorder which, in the opinion of the investigator, may either put the subject at risk because of participation in the study, or influence the results or the subject's ability to participate in the study
• - History or presence of gastrointestinal, mental, cardiac, hepatic or renal disorder, or any other condition known to interfere with absorption, distribution, metabolism or excretion of drugs
• - Abnormal vital signs, after 10 minutes supine rest
• - Any clinically significant illness, medical/surgical procedure or trauma within 4 weeks of the administration of IP
• - Any clinically significant abnormalities in clinical chemistry, haematology or urinalysis results as judged by the investigator