A double blind randomised placebo-controlled crossover (single centre) study in healthy men (aged 18-45 years) to investigate the effect of multiple dosing (7 days bid) of inhaled AZD4818 at different dose levels on white blood cells and inflammatory markers in induced sputum and blood after oral inhalation of lipopolysaccharide (LPS)

Study identifier:D3540C00004

ClinicalTrials.gov identifier:N/A

EudraCT identifier:N/A

CTIS identifier:N/A

Study Complete

Official Title

A double blind randomised placebo-controlled crossover (single centre) study in healthy men (aged 18-45 years) to investigate the effect of multiple dosing (7 days bid) of inhaled AZD4818 at different dose levels on white blood cells and inflammatory markers in induced sputum and blood after oral inhalation of lipopolysaccharide (LPS)

Medical condition

Chronic Obstructive Pulmonary Disease

Phase

Phase 1

Healthy volunteers

-

Study drug

-

Sex

-

Actual Enrollment

-

Study type

Interventional

Age

-

Date

Study Start Date: 01 Jan 2008
Primary Completion Date: -
Study Completion Date: -

Study design

Allocation: -
Endpoint Classification: -
Intervention Model: -
Masking: -
Primary Purpose: -

Verification:

Verified 01 Nov 2013 by AstraZeneca

Sponsors

AstraZeneca

Collaborators

-

Inclusion and exclusion criteria