Safety, Pharmacokinetics and Pharmacodynamics after single and multiple dosing of AZD5423 in Japanese healthy male subjects

Study identifier:D2340C00003

ClinicalTrials.gov identifier:N/A

EudraCT identifier:N/A

CTIS identifier:N/A

Study Complete

Official Title

A phase I, Single Centre, Double-blind, Randomised, Placebo-controlled, Parallel-group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Inhaled AZD5423 after Administration of Single and Multiple Ascending Doses in Healthy Male Japanese Subjects

Medical condition

Healthy

Phase

Phase 1

Healthy volunteers

Yes

Study drug

AZD5423, Placebo

Sex

Male

Actual Enrollment

96

Study type

Interventional

Age

20 Years - 45 Years

Date

Study Start Date: 01 Jun 2011
Primary Completion Date: 01 Dec 2011
Study Completion Date: 01 Dec 2011

Study design

Allocation: Randomized
Endpoint Classification: Pharmacodynamics Study
Intervention Model: Parallel Assignment
Masking: Double Blind
Primary Purpose: Basic Science

Verification:

Verified 01 Jan 2015 by AstraZeneca Pharmaceuticals

Sponsors

AstraZeneca Pharmaceuticals

Collaborators

-

Inclusion and exclusion criteria