Pharmacokinetics of extended-release test- and reference formulations of AZD0837

Exclusion Criteria

• - Significant illness (including ongoing or history of liver disease), trauma or surgical procedures from 2 weeks before the pre-entry visit until the first administration of Investigational Product
• - Clinical significant abnormalities in clinical chemistry, haematology or urinalysis result including positive result on screening tests for serum hepatitis B surface antigen, hepatitis C antibody or HIV or positive F-Hb result pre-entry
• - History of bleeding disturbance (including extensive menstrual bleedings) or thrombotic disorder
• - Clinically significant medical history, as judged by the investigator, including psychiatric disorders or severe allergies.