AZD7268 Single Ascending Dose Study in Healthy Japanese Subjects - JSAD

Exclusion Criteria

• - Clinically relevant disease or disorder (past or present), which in the
• opinion of the investigator, may either put the subject at risk because of
• participation in the study or influence the results or the subject’s
• ability to participate in the study
• - Any clinically significant abnormalities in physical examination, vital
• signs, clinical chemistry, hematology or urinalysis results as judged by
• the investigator and/or sponsor
• - Smoking in excess of 5 cigarettes per day or equivalent within 30 days of
• Day 1