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An Open-label, Sequential, 3-period Study to Assess the Effects of Cimetidine on the Pharmacokinetics of Naloxegol in Healthy Volunteers.
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An exploratory, double-blind, randomized, placebo controlled, 2 period cross-over, pharmacokinetic/pharmacodynamic, single center study to asses the effect of AZD6140 on respiratory parameters in mild asthma and mild COPD patients age 55 to 75 years
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An exploratory, double-blind, placebo controlled, 2 period cross-over, 3 cohort, single center, pharmacodynamic study to assess the effect of AZD6140 on respiratory parameters in healthy subjects, mild asthmatics and COPD patients age 40 to 70 years.
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A Phase I, Open-label, Multiple-dose, Dose-escalation Study To Assess the Safety, Tolerability and Pharmacokinetics of AZD8931 in Patients with Advanced Solid Malignancies
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A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients with Irritable Bowel Syndrome with Constipation (IBS-C)
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PROstaTE Cancer Treatment and Obesity in Zoladex-Astrazeneca Treated patients Assesment of the correlation between Body Mass Index and recurrence among Zoladex treated prostate cancer patients
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A Double-blind Placebo-controlled, Randomised, Single centre, First Time in Man Study to evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Inhaled Doses of AZD7624 in Healthy Subjects
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A Randomised, Double-Blind, 2-Period Crossover Study to Assess the Effect of Steady-State AZD6140 on the Pharmacokinetics of a Single Oral 500-mg Dose of Tolbutamide, a Substrate of CYP2C9, in Healthy Male and Female Volunteers.
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A Phase I/II Multi-centre Study of AZD8931 in Combination with Weekly Paclitaxel to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy in Patients with Advanced Solid Tumours and in a Selected Population with Low HER2-expressing Locally Recurrent and/or Metastatic Breast Cancer (THYME)
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A Phase 1, Single Centre, Double-blind, Randomised, Placebo-controlled, Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics after Administration of Multiple Ascending (MAD) Once Weekly Inhaled Doses of AZD8848 in Healthy Subjects
