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The following trials provide information to treat various types of disease of the brain and the central and local nervous systems, both for ongoing and completed clinical trials.  For more information on this therapy area please click here.

There are a number of ways to help you find trial information.  By using these filters you can find (i) recruiting status, (ii) therapy area, (iii) product and/or (iv) phase of drug development.  You can use one or all filters to identify your specific needs.

When a trial completes the results are reported here no later than one year after completion – this is why you may sometimes find that a Report is unavailable when you are searching through ‘closed’ trials.

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  • collapse A Canadian Multicentre, Open-label, Prospective Long-term Study Evaluating the Clinical Benefit and Effectiveness of Sustained-release Quetiapine Fumarate (SEROQUEL) in Patients with Schizophrenia.
  • collapse A Multi-Center, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Extended-Release (Seroquel XRTM) as Mono-Therapy in the Treatment of Elderly Patients with Major Depressive Disorder (SAPPHIRE STUDY)
  • collapse A Multi-Center, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Extended-Release (Seroquel XRTM) as Monotherapy in the Treatment of Elderly Patients with Generalized Anxiety Disorder (CHROMIUM STUDY)
  • collapse An International, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled, Active-controlled Study of the Efficacy and Safety of Sustained-release Quetiapine Fumarate (Seroquel SR) in the Treatment of Generalized Anxiety Disorder (SILVER Study)
  • collapse A Multicenter, Randomized, Double-blind, Parallel-group, Placebocontrolled, Active-controlled Study of the Efficacy and Safety of ustainedrelease Quetiapine Fumarate (SEROQUEL) Compared with Placebo in the Treatment of Generalized Anxiety Disorder (Gold Study)
  • collapse An 8-week, Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled Study of the Efficacy and Safety of Quetiaine Fumarate (Seroquel) 50, 150, and 300 mg/day Compared with Placebo in the Treatment of Generalised Anxiety Disorder
  • collapse A Multicenter, Double-blind, Randomized-Withdrawal, Parallel-group, Placebo-controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Sustained Release (Seroquel SR) as Monotherapy in the Maintenance Treatment of Patients with Generalized Anxiety Disorder Following an Open-Label Stabilization Period (PLATINUM STUDY)
  • collapse A Multicenter, Double-blind, Randomized, Parallel-group, Placebocontrolled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Extended-release (SEROQUEL XR) in Combination with an Antidepressant in the Treatment of Patients with Major Depressive Disorder with Inadequate Response to an Antidepressant Treatment (Onyx Study)
  • collapse A Multicenter, Double-blind, Randomized, Parallel-group, Placebocontrolled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Extended-release (SEROQUEL XR) in Combination with an Antidepressant in the Treatment of Patients with Major Depressive Disorder with Inadequate Response to an Antidepressant Treatment (Pearl Study)
  • collapse A Multicenter, Double-blind, Randomized-withdrawal, Parallel-group, Placebo-controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (SEROQUEL XR) as Monotherapy in the Maintenance Treatment of Patients with Major Depressive Disorder Following an Open-Label Stabilization Period (AMETHYST STUDY)
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