The following trials provide information to treat various types of disease of the brain and the central and local nervous systems, both for ongoing and completed clinical trials. For more information on this therapy area please click here.
- collapse A Phase I, Single-centre, Randomised, Double-blind, Placebo-controlled Parallel group Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD2066 in Young and Elderly Healthy Volunteers after Oral Single Ascending Doses.
- collapse A Phase I, single center, randomized, double-blind, placebo-controlled parallel-group study to assess the safety, tolerability and pharmacokinetics of single and multiple ascending doses of TC-5214 in Japanese healthy elderly male and female volunteers
- collapse The purpose of this study is to assess the safety and effect of TC-5214 as a single therapy in patients with major depressive disorder who exhibit inadequate response to antidepressants.
- collapse Phase I, Open-label, Randomized, Single-dose, Two treatment (Fed Versus Fasted) Crossover Study to Assess the Effects of Food on the Pharmacokinetics of TC-5214 (S-Mecamylamine) in Healthy Subjects
- collapse A Phase I, single centre, randomised, double-blind, placebo-controlled study to assess the safety, tolerability and pharmacokinetics of a single dose and multiple doses of TC-5214 (S-Mecamylamine) in healthy male Japanese subjects
- collapse A Phase I, Single-centre, Randomised, Double-blind, Parallel Group, Placebo-controlled Study to Assess the Safety, Tolerability and Pharmacokinetics after Multiple Oral Doses of AZD2066 in Japanese Healthy Male Subjects
- collapse An Open Label, Non-randomized Positron Emission Tomography (PET) Study With [11C]AZ12713580 to Determine Central mGluR5 Receptor Occupancy of AZD2066 After Oral Administration to Healthy Subjects.
- collapse A Phase IIa, Double-Blind, Randomised, Parallel-Group, Multi-Centre Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy
- collapse Investigation of Rate + Extent of Excretion of Radioactivity in Urine +Faeces After Oral Administration of [14C]AZD2066.
- collapse An Open label, Single dose, Phase I study of the Excretion of Radioactivity, Metabolism and Pharmacokinetics following Oral administration of [14C] AZD2066 to Healthy Male Subjects
