The following trials provide information to treat various types of disease of the brain and the central and local nervous systems, both for ongoing and completed clinical trials. For more information on this therapy area please click here.
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A single-centre, randomised, double-blind, placebo controlled Phase I study in two parts: Part A to assess a safe and tolerable supratherapeutic dose of TC-5214 after single ascending oral doses in healthy male subjects, followed by Part B: A four-period double-dummy crossover study to investigate the effect of 2 single doses (therapeutic and supratherapeutic) of TC-5214 on the QT/QTc interval, compared to placebo, using moxifloxacin (Avelox®) as a positive control, in healthy male subjects.
- Study Id
- D4130C00009
- Disease
- drug safety, pharmacokinetics
- Drug Name
- AstraZeneca Neuroscience Development Drugs
- Study Name
- D4130C00009
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Dec 27, 2012
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A non – interventional study to Investigating the ratio of Mis-diagnosed bipolar symptoms in Patient diagnosed as with treatment Resistant major depressive disorder (MDD).
- Study Id
- NIS-NIT-DUM-2010/1
- Disease
- depressive disorder
- Drug Name
- non drug study (neuroscience)
- Study Name
- NIS-NIT-DUM-2010/1
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Jan 28, 2013
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A Multicenter, Randomized, Double-Blind, Parallel Group, Placebo-Controlled, Phase III Efficacy and Safety Study of TC-5214 (S-mecamylamine) in Flexible Doses as an Adjunct to an Antidepressant in Patients with Major Depressive Disorder with an Inadequate Response to Antidepressant Therapy
- Study Id
- D4130C00002
- Disease
- depressive disorder
- Drug Name
- TC-5214
- Study Name
- D4130C00002
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Jun 18, 2012
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RECONNECT-S ALPHA: A Non-interventional Study to Observe Real-life Allocation of Antipsychotics in the Acute Inpatient Management of Schizophrenia
- Study Id
- NIS-NRU-ATC-2011/1
- Disease
- schizophrenia
- Drug Name
- non drug study (neuroscience)
- Study Name
- RECONNECT-S
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Nov 16, 2012
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Prospective, observational study for the maintenance treatment of patients with Bipolar Disorder I and II in Greece.
- Study Id
- NIS-NGR-DUM-2010/1
- Disease
- bipolar disorder
- Drug Name
- non drug study (neuroscience)
- Study Name
- NIS-NGR-DUM-2010/1
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Sep 3, 2012
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An Investigation of the Antidepressant Efficacy of a Selective, High, Affinity Enkephalinergic Agonist in Anxious Major Depressive Disorder
- Study Id
- D0880C00021
- Disease
- anxiety, depression
- Drug Name
- AZD2327
- Study Name
- D0880C00021
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Sep 7, 2012
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IBIS: Italian Burden of Illness on Schizophrenia & bipolar disorder
- Study Id
- NIS-NIT-XXX-2011/1
- Disease
- schizophrenia
- Drug Name
- non drug study (neuroscience)
- Study Name
- IBIS
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Sep 15, 2012
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Seroquel XR in the long term treatment of schizophrenia focus on affective symptoms
- Study Id
- NIS-NHU-SER-2010/1
- Disease
- schizophrenia
- Drug Name
- Seroquel XR
- Study Name
- NIS-NHU-SER-2010/1
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Sep 25, 2012
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A Phase I, Single-centre, Randomised, Double-blind, Placebo-controlled,
Parallel Group Study to Assess the Safety, Tolerability and Pharmacokinetics after Single Ascending Oral Doses of AZD2066 in Japanese Healthy Male Subjects.
- Study Id
- D0475C00003
- Disease
- pharmacokinetics, safety
- Drug Name
- AstraZeneca Neuroscience Development Drugs
- Study Name
- D0475C00003
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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Sep 12, 2008
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A Phase I, Single-centre, Randomised, Double-blind, Placebo-controlled Parallel group Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD2066 in Young and Elderly Healthy Volunteers after Oral Single Ascending Doses.
- Study Id
- D0475C00001
- Disease
- pharmacokinetics, safety
- Drug Name
- AstraZeneca Neuroscience Development Drugs
- Study Name
- D0475C00001
- Recruiting Status
- Closed
- Protocol Status
- Not Available
- Report
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May 7, 2008
