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The following trials provide information to treat various types of disease of the brain and the central and local nervous systems, both for ongoing and completed clinical trials.  For more information on this therapy area please click here.

There are a number of ways to help you find trial information.  By using these filters you can find (i) recruiting status, (ii) therapy area, (iii) product and/or (iv) phase of drug development.  You can use one or all filters to identify your specific needs.

When a trial completes the results are reported here no later than one year after completion – this is why you may sometimes find that a Report is unavailable when you are searching through ‘closed’ trials.

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  • expand A Phase I, Randomised, Double-blind, Placebo-controlled, Parallel Group Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1446 in Male and Non-fertile Female, young and Elderly Healthy Volunteers, After Oral Multiple Ascending Doses
    Study Id
    D1950C00002
    Disease
    Alzheimer's Disease
    Drug Name
    AZD1446
    Study Name
    D1950C00002
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand A Phase I, Randomised, Double-blind, Placebo-controlled, Parallel-group Single Ascending Dose Study to Asses the Safety, Tolerability, Pharmacokinetics of AZD1446 including an Open Food Effect Panel in Healthy Male and Non-fertile Female Volunteers
    Study Id
    D1950C00001
    Disease
    Alzheimer's Disease
    Drug Name
    AZD1446
    Study Name
    D1950C00001
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand Open label Positron Emission Tomography (PET) study with [11C]AZD2995 and [11C]AZD2184, candidate PET ligands for ß amyloid, to determine and compare in vivo brain uptake and distribution in healthy volunteers and patients with Alzheimer’s Disease
    Study Id
    D0180C00018
    Disease
    Alzheimer's Disease
    Drug Name
    AstraZeneca Neuroscience Development Drugs
    Study Name
    D0180C00018
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand A Phase IIa randomised, double-blind, placebo controlled, parallel group, multicentre study evaluating the efficacy, safety, tolerability and pharmacokinetics of AZD1386 after 3 weeks of treatment in patients with Posttraumatic Neuralgia (PTN) and Postherpetic Neuralgia (PHN)
    Study Id
    D5090C00018
    Disease
    analgaesia
    Drug Name
    AZD1386
    Study Name
    D5090C00018
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand A Randomised, Double-Blind, Placebo-Controlled, Single-Centre Study to Determine the Effect of Intradermal AZD3161 on Quantitative Sensory Testing Variables in Normal and UVC Exposed Skin in Healthy Volunteers
    Study Id
    D3780C00005
    Study Name
    D3780C00005
    Recruiting Status
    Not Yet Recruiting
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand An Open, Two Period, Single Dose, Phase I Study of the Excretion of Radioactivity, Metabolic Profiles and Pharmacokinetics Following Oral Administration of [14C]-AZD3480 and the Pharmacokinetics of AZD3480 Following Intravenous Administration to Healthy Male Volunteers with Different CYP2D6 Genotype
    Study Id
    D3690C00017
    Disease
    schizophrenia, Alzheimer's Disease
    Drug Name
    AZD3480
    Study Name
    D3690C00017
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand An Open Label, Single Dose, Phase I Study to Evaluate the Excretion of Radioactivity, the Metabolic Profile, Pharmacokinetics, Safety and Tolerability Following Single Oral Administration of [14C]AZD2423 to Healthy Male Volunteers
    Study Id
    D2600C00008
    Drug Name
    AZD2423
    Study Name
    D2600C00008
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand A Phase IIa, Multi-center, Randomized, Double-blind, Placebo-controlled, Cross-Over Study to Assess the Efficacy, Safety ,tolerability and Pharmacokinetics of Three Oral AZD1446 Dose Regimens and Placebo During 2 weeks of Treatment in Adult Non-Users and users of Nicotine Containing Products
    Study Id
    D1950C00007
    Disease
    Alzheimer's Disease
    Drug Name
    AZD1446
    Study Name
    D1950C00007
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand Explorative trial of AZD3480 - ADHD
    Study Id
    TC-1734-226-CRD-005
    Disease
    schizophrenia, Alzheimer's Disease
    Drug Name
    AZD3480
    Study Name
    TC-1734-226-CRD-005
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
  • expand Unraveling the Relation of Patient's Profile and Therapeutical Effects of Atypicals, Including Quetiapine Effect
    Study Id
    NL-401241
    Disease
    schizophrenia
    Drug Name
    Seroquel
    Study Name
    NL-401241
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report Status
    Not Available
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