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The following trials provide information to treat various types of gastrointestinal diseases, both for ongoing and completed clinical trials.  For more information on this therapy area please click here.

There are a number of ways to help you find trial information.  By using these filters you can find (i) recruiting status, (ii) therapy area, (iii) product and/or (iv) phase of drug development.  You can use one or all filters to identify your specific needs.

When a trial completes the results are reported here no later than one year after completion – this is why you may sometimes find that a Report is unavailable when you are searching through ‘closed’ trials.

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  • collapse A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment with Esomeprazole 20 mg qd to Placebo qd in Patients with Heartburn and Sleep Disturbances Associated with Gastroesophageal Reflux Disease (GERD)
  • collapse An open label, multicentre study of Nexium (esomeprazole) 40 mg once daily in subjects with symptoms of Gastroesophageal Reflux Disease (GORD) after treatment with a full dose of Proton Pump Inhibitor (PPI) - NEON
  • collapse A cross-sectional, Canadian, multi-centre study of symptom burden and clinical management in subjects with Gastroesophageal Reflux Disease (GERD) RANGE: Retrospective ANalysis of GErd
  • collapse Evaluation of the efficacy of three strategies of long-term management of symptoms of gastroesophageal reflux in general medicine: a multicentre, randomised, open label study conducted in parallel groups.
  • collapse SYMPATHY (Symptom Adapted Therapy) A randomised, open, parallel-group, multi-national, multi-centre, phase IV study to evaluate the efficacy of three different subject management strategies with and without esomeprazole 20 mg during a 3 months maintenance phase following an initial 4-weeks acute treatment phase in subjects with symptoms thought to be GERD related
  • collapse An Open-Label, Exploratory Trial to Assess Gastric Acid Control in Critically Ill Subjects Receiving Nexium I.V. (esomeprazole sodium) 40 mg BID for up to 72 hours
  • collapse A Randomized, Open-Label, Comparative 3-way Crossover Study of 24-hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40 mg, Lansoprazole 30 mg, and Pantoprazole 40 mg at Steady State in Hispanic Patients with Symptomatic GERD
  • collapse A study to assess the effectiveness of Esomeprazole 40 mg once daily patients with continuing Gastroesophageal Reflux Disease (GORD) following treatment with a previous full dose Proton Pump Inhibitor An 8 week, open label, multicentre study. (RESPONSE Study)
  • collapse Nexium in patients submitted to a gastric by-pass surgery
  • collapse Examine National Characteristics & Outcome Measures of GERD Patients Using the PPI Acid Suppression Symptom (PASS) Test for Response
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