The following trials provide information to treat various types of cardiovascular diseases, both for ongoing and completed clinical trials. For more information on this therapy area please click here.
- collapse A phase I, open-label, pharmacokinetic study measuring plasma exposure of a 20 mg single dose administration of rosuvastatin calcium to healthy Asian subjects living in the United States related to the pharmacokinetic data obtained from a Caucasian control group
- collapse A randomized, open-label, 2 way crossover study to assess the reciprocal effects of co-administration of rosuvastatin 40 mg and ezetimibe 10 mg on the steady-state pharmacokinetics of each drug
- collapse A 26-week, double blind, randomised, mulit-centre, phase IIIb, parallel group study to compare the efficacy and safety of rosuvastatin (40 mg) with atorvastatin (80 mg) in subjects with hypercholesterolaemia and coronary heart disease or CHD risk equivalents.
- collapse A 24-week, randomised, open-label, parallel-group, multi-centre study which compares the efficacy and safety of rosuvastatin 10, 20 and 40 mg with atorvastatin 10, 20 40 and 80 mg when force titrated in the treatment of patients with primary hypercholesterolemia and either a history of coronary heart disease (CHD) or clinical evidence of atherosclerosis or a CHD risk equivalent (10 year risk score >20%).
- collapse A Randomized, Double-blind, Placebo-controlled, Multicenter Parallel Group Phase III Study Measuring Effects on Intima Media Thickness: An Evaluation Of Rosuvastatin 40 mg (METEOR)
- collapse A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID) A 104-Week, Open-label, Multi-center, Phase IIIb Study Evaluating the Effect of Treatment with Rosuvastatin 40 mg on Atherosclerotic Disease as Measured by Intravascular Ultrasound and Quantitative Coronary Angiography in Subjects Undergoing Coronary Angiography who have Coronary Artery Disease
- collapse A Randomised, Double-Blind, Placebo Controlled, Crossover Study to Assess the Effect of ZD4522 on the Incorporation of Trideuterated Leucine into Lipid Subfractions & Apolipoproteins in Subjects with Mild to Moderate Hyperlipidaemia.
- collapse An 8-week randomized double blind placebo controlled multicenter trial to evaluate the effects of Rosucastatin 40 mg on Myocardail Ischemia in subjects with coronary artery disease.
- collapse Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)
- collapse Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)
