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Cardiovascular
The following trials provide information to treat various types of cardiovascular diseases, both for ongoing and completed clinical trials. For more information on this therapy area please click here.
- collapse A single-blind, randomized, placebo controlled phase I study to investigate the effect of single oral doses of AZD1175 with and without food on safety, tolerability and pharmacokinetics
- collapse An Open label, Pharmacokinetic Study of Single and Multiple Doses of 5 mg Saxagliptin in Healthy Chinese Subjects Living in China
- collapse An 18-week, International, Multi-centre, Randomized, Parallel-group, Double-Blind, Active-Controlled Phase IIIb Study to Evaluate the Efficacy and Safety of Saxagliptin in combination with Metformin in Comparison with Sitagliptin in combination with Metformin in Adult Patients with Type 2 Diabetes Who Have Inadequate Glycaemic Control on Metformin Therapy alone
- collapse A double-blind, randomised, placebo-controlled, parallel-group, multicentre, phase II study to assess the efficacy of AZD7009 (AR H065522XX) given intravenously (infusion for 15 or 30 minutes) to patients for conversion of atrial fibrillation.
- collapse A multicenter, randomized, double-blind, parallel-group, dose titration (10 mg and 20 mg) study to compare the efficacy and safety of Rosuvastatin versus Atorvastatin in patients with primary hypercholesterolemia
- collapse A 6-week Open-label, Randomised, Multicentre, Phase IIIb, Parallel-group Study to Compare the Efficacy and Safety of Rosuvastatin (10 mg) with Atorvastatin (20 mg) in Subjects with Hypercholesterolaemia and Either a History of Coronary Heart Disease (CHD) or Clinical Evidence of Atherosclerosis or a CHD Risk Equivalent (10-year Risk Score of >20%) PULSAR – A Prospective study to evaluate the Utility of Low doses of the Statins Atorvastatin and Rosuvastatin.
- collapse A Phase I, Single Center, Randomized, Double-blind, Placebo-controlled, 2-Way Crossover Trial to Assess the Effect of Gemfibrozil on the Pharmacokinetics of a Single Oral Dose of Rosuvastatin 80 mg in Healthy Men and Women
- collapse A Single Centre, Randomised, Double-blind, 2-Way Crossover Trial to Assess the Effect of Erythromycin, a CYP3A4 Inhibitor, on the Pharmacokinetics of a Single Oral Dose of ZD4522 80 mg in Healthy Male Volunteers
- collapse A Single Centre, Randomised, Double-blind, 2-Way Crossover Trial to Assess the Effect of Ketoconazole, a CYP3A4 Inhibitor, on the Pharmacokinetics of a Single Oral Dose of ZD4522 80 mg in Healthy Male Volunteers
- collapse A Randomised, Double-Blind, Dose-Response Study with the HMG-CoA Reductase Inhibitor ZD4522 in Subjects with Hyperlipidaemis (A Phase II Clinical Study)
