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  • Cardiovascular

The following trials provide information to treat various types of cardiovascular diseases, both for ongoing and completed clinical trials.  For more information on this therapy area please click here.

There are a number of ways to help you find trial information.  By using these filters you can find (i) recruiting status, (ii) therapy area, (iii) product and/or (iv) phase of drug development.  You can use one or all filters to identify your specific needs.

When a trial completes the results are reported here no later than one year after completion – this is why you may sometimes find that a Report is unavailable when you are searching through ‘closed’ trials.

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  • expand A 24-week, multicentre, randomised, double-blind,age-stratified, placebo controlled phase III study with an 80-week extension period to evaluate the efficacy and safety of dapagliflozin 10 mg /day in patients with T2DM and cardiovascular disease, who exhibit inadequate glycaemic control on usual care
    Study Id
    D1690C00019
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1690C00019
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Oct 13, 2011
    • D1690C00019.pdf (197 KB)
  • expand A 24-week, multicentre, randomised, double-blind, age-stratified, placebo controlled, phase III study with a 80-week extension period to evaluate the efficacy and safety of dapagliflozin 10 mg/day in pts with T2DM, CV disease and hypertension who exhibit inadequate glycaemic control on usual care
    Study Id
    D1690C00018
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1690C00018
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Oct 13, 2011
    • D1690C00018.pdf (176 KB)
  • expand A 24-week,Multicentre,Randomised,Double-Blind,Placebo-Contr,Parallel-Group,International Phase III Study with 24week Extension to Evaluate the Safety and Efficacy of Dapagliflozin 10 mg/Day in patients with Type 2 Diabetes who have Inadequate Glyc Control on a DPP-4 inhibitor Sitagliptin+/-Metformin
    Study Id
    D1690C00010
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1690C00010
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    May 28, 2012
    • D1690C00010.pdf (199 KB)
  • expand A 24-week international, randomized, parallel-group, double-blind, placebo-controlled Phase III study with a 24-week extension period to evaluate the efficacy and safety of dapagliflozin therapy when added to the therapy of patients with type 2 diabetes with inadequate glycaemic control on insulin
    Study Id
    D1690C00006
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1690C00006
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Sep 16, 2010
    • D1690C00006.pdf (144 KB)
  • expand A 24-Week,Int.,Rand.,Double-blind,Parallel-group,Multi-centre, Plac.-controlled Phase III Study with a 24-Wk Ext.Per.to Eval.the Efficacy and Safety of Dapagliflozin in Comb.with Glimepiride (a Sulphonylurea) in Subjects with Type2 Diab.who Have Inadeq. Glycaemic Control on Glimepiride Therapy Alone
    Study Id
    D1690C00005
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1690C00005
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Sep 7, 2012
    • D1690C00005.pdf (144 KB)
  • expand Drug-drug Interaction Study of Dapagliflozin With Voglibose in Japanese Type 2 Diabetes Mellitus Patients
    Study Id
    D1692C00002
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1692C00002
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Aug 16, 2010
    • D1692C00002.pdf (494 KB)
  • expand An open label, randomized, two-period, crossover study to assess the effect of food on fixed dose combination dapagliflozin/metformin tablet (5 mg/1000 mg) in healthy male and female volunteers
    Study Id
    D1691C00005
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1691C00005
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Dec 3, 2010
    • D1691C00005.pdf (96 KB)
  • expand A Study Comparing the Amount of Metformin and After Taking a Combination Tablet vs. Separate Tablets
    Study Id
    D1691C00002
    Disease
    diabetes mellitus
    Drug Name
    dapagliflozin
    Study Name
    D1691C00002
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Aug 4, 2010
    • D1691C00002.pdf (127 KB)
  • expand An epidemiological study to evaluate standard daily practice in managing patients with arterial hypertension and to evaluate patients’ quality of life
    Study Id
    NIS-CRS-DUM-2010/2
    Disease
    hypertension
    Drug Name
    non drug study (cardiovascular)
    Study Name
    NIS-CRS-DUM-2010/2
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Jun 30, 2012
    • NIS-CRS-DUM-2010/2.pdf (149 KB)
  • expand A Randomised, Open Label, Parallel Group, Multicentre, Phase IV Study on the Effect of 8 Weeks Succinate Metoprolol (Betaloc ZOK®) (95 - 190 mg) on Heart Rate in the Stable Angina Patients
    Study Id
    D4022L00008
    Disease
    unstable angina pectoris
    Drug Name
    metoprolol succinate
    Study Name
    D4022L00008
    Recruiting Status
    Closed
    Protocol Status
    Not Available
    Report
    Jul 10, 2012
    • D4022L00008.pdf (571 KB)
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