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The following trials provide information to treat various types of cardiovascular diseases, both for ongoing and completed clinical trials.  For more information on this therapy area please click here.

There are a number of ways to help you find trial information.  By using these filters you can find (i) recruiting status, (ii) therapy area, (iii) product and/or (iv) phase of drug development.  You can use one or all filters to identify your specific needs.

When a trial completes the results are reported here no later than one year after completion – this is why you may sometimes find that a Report is unavailable when you are searching through ‘closed’ trials.

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  • collapse IRS-CD2-Safety, tolerability
  • collapse A double-blind, randomised, two-way crossover single-centre pharmacokinetic interaction (phase I) study of repeated oral doses of AZ 242 (3 mg) and a single oral dose of warfarin (25 mg) in healthy male subjects
  • collapse A phase I study to investigate the safety and pharmacokinetics of AZ242 after repeated oral dosing (3 mg once daily) in healthy male Japanese subjects (single-blind, rondomized, placebo-controlled, parallel group study)
  • collapse A single-centre, open, randomised, three-way crossover drug-drug interaction study of AZ 242 8 mg and glibenclamide 3.5 mg after single oral administration in healthy male subjects (Phase I)
  • collapse A single-centre, open, randomised, two-way crossover, phase I interaction study to assess the effects of ketoconazole 200 mg once daily on the pharmacokinetics of a single dose of AZ 242 8 mg, when administered to healthy male subjects
  • collapse A double-blind, randomised, single-centre, placebo-controlled, cross-over phase I study to investigate renal function in healthy male subjects, after repeated oral dosing of 3 mg AZ 242
  • collapse A single-centre, open, randomised, three-way crossover drug-drug interaction study of AZ 242 tablet 3 mg and metformin tablet 500 mg bid after repeated oral administration in healthy male subjects (Phase I) Author: Eric Evene, Aster
  • collapse A single-centre, open, randomised, three-way crossover drug-drug interaction study of AZ 242 tablet 3 mg and digoxin tablet 0.25 mg after repeated oral administration in healthy male subjects (Phase I)
  • collapse A Study to investigate the effect of food on PK and safety of AZ242 (single oreal dose of 3 mg) in healthy male Japanese subjects
  • collapse IRS-CD2-kidney
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