The following trials provide information to treat various types of cardiovascular diseases, both for ongoing and completed clinical trials. For more information on this therapy area please click here.
- collapse Perceived hypoglycemia- and weight-related Quality of Life of patients with sulfonylurea derivate-treated Diabetes Mellitus Type 2, a non-interventional study.
- collapse A 24-week, Multi-centre, International, Double-blind, Randomized, Parallel-group, Placebo-controlled, Phase III Study with a 78-week Extension Period to Evaluate the Effect of Dapagliflozin in Combination with Metformin on Body Weight in Subjects with Type 2 Diabetes Mellitus Who Have Inadequate Glycaemic Control on Metformin Alone
- collapse A 24-week randomised, double-blind, parallel-group, multi-centre, placebo-controlled phase III trial to evaluate the efficacy and safety of dapagliflozin as monotherapy in Japanese subjects with Type 2 diabetes who have inadequate glycemic control with diet and exercise
- collapse An open label, randomized, two-period, crossover study to assess the effect of dapagliflozin on percent inhibition of glucose reabsorption when administered once a day (10 mg QD) versus twice a day (5 mg BID) in healthy male and female volunteers
- collapse A 52-Week International, Multi-centre, Randomised, Parallel-group, Double-blind, Active-controlled, Phase III study with a 52-Week Extension Period to Evaluate the Efficacy and Safety of Dapagliflozin in Combination with Metformin compared with Sulphonylurea in Adult Patients with Type 2 Diabetes
- collapse A multicenter, randomized, double-blind, placebo-controlled, parallel group, Phase 2 trial to evaluate the efficacy and safety of dapagliflozin as monotherapy in Japanese subjects with type 2 diabetes mellitus who have inadequate glycemic
- collapse A 16-week, Multicentre, Randomised, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Safety and Efficacy of Dapagliflozin 2.5 mg BID, 5 mg BID and 10 mg QD Versus Placebo in Patients With Type 2 Diabetes Who Are Inadequately Controlled on Metformin-IR Monotherapy
- collapse A double-blind, randomized, four-period crossover study to assess the effects of single oral dose Dapagliflozin administration on QTc interval compared to placebo, using AVELOX (moxifloxacin) as a positive control, in healthy male volunteers age 18 to 45 years
- collapse A Phase I, Single Centre, Single-blind, Randomised, Placebo-controlled, Parallel-group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of oral AZD7687 after Administration of Single and Multiple Ascending Doses in Healthy Male Japanese Subjects
- collapse A Phase 1, Single Centre, Single-Blind, Randomised, Placebo-controlled, Parallel-group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZD7687 After Administration of Multiple Ascending Doses in Overweight to Obese But Otherwise Healthy Male Subjects
